TMEM187

Across TCGA patient cohorts, TMEM187 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,138 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM187-associated GO terms across cancer lineages are Peroxisome fission, Fatty-acyl-CoA catabolic process, and Peroxisome organization. Each is linked with TMEM187 in more than 19 cancer types. Because this analysis shows association rather than direction, both TMEM187-to-partner and partner-to-TMEM187 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peroxisome fission grouped by TMEM187-low versus TMEM187-high in READ.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM187→partner) and Y-score (partner→TMEM187) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	Peroxisome fission →	+0.057	+0.723	<.001	<.001	3	18
SCLC	Fatty-acyl-CoA catabolic process →	+0.681	+0.515	.002	.001	1	20
UVM	Peroxisome organization →	+0.040	+0.586	<.001	<.001	3	15
LAML	Organic acid catabolic process →	+0.033	+0.641	<.001	<.001	3	15
ACC	Monocarboxylic acid catabolic process →	+0.032	+1.088	<.001	<.001	2	16
ACC	Short-chain fatty acid metabolic process →	+0.060	+1.281	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,138 associations by consensus.

Peroxisome fission by TMEM187 expression — READ

Explore this box plot interactively →