TMEM187

Across TCGA cell cohorts, TMEM187 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,078 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM187-associated GO terms across cancer lineages are Macroautophagy, Monocarboxylic acid catabolic process, and Glycerophospholipid metabolic process. Each is linked with TMEM187 in more than 8 cancer types. Because this analysis shows association rather than direction, both TMEM187-to-partner and partner-to-TMEM187 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by TMEM187-low versus TMEM187-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM187→partner) and Y-score (partner→TMEM187) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Macroautophagy →	+0.034	+0.688	.002	.004	3	9
BLOOD_Lymphoma	Monocarboxylic acid catabolic process →	+0.037	+0.661	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Glycerophospholipid metabolic process →	+0.042	+0.942	<.001	<.001	3	8
BLOOD_Myeloma	Transcription elongation by RNA polymerase I →	-0.104	-0.653	<.001	<.001	3	8
OESOPHAGUS	Lipid modification →	+0.046	+1.024	.003	<.001	2	9
CNS	Negative regulation of autophagy →	+0.062	+0.708	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,078 associations by consensus.

Macroautophagy by TMEM187 expression — SKIN

Explore this box plot interactively →