TMEM187

Across TCGA cell cohorts, TMEM187 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM187-associated genes across cancer lineages are LCE1F and OR51G2. Each is linked with TMEM187 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM187-to-partner and partner-to-TMEM187 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCE1F grouped by TMEM187-low versus TMEM187-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM187→partner) and Y-score (partner→TMEM187) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LCE1F →	+0.224	+5.415	<.001	.004	3	1
BLOOD_Leukemia	OR51G2 →	+0.022	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

LCE1F by TMEM187 expression — LARGE_INTESTINE

Explore this box plot interactively →