Across TCGA patient cohorts, TMEM186 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,263 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM186-associated proteins across cancer lineages are DCTPP1, JPT2, and NUDT16L1. Each is linked with TMEM186 in more than 7 cancer types. Because this analysis shows association rather than direction, both TMEM186-to-partner and partner-to-TMEM186 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM186→partner) and Y-score (partner→TMEM186) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DCTPP1 →	+0.840	+0.688	<.001	<.001	3	8
OV	JPT2 →	+0.351	+0.705	<.001	<.001	3	6
OV	NUDT16L1 →	+0.370	+0.543	<.001	<.001	3	6
LSCC	GTF3C4 →	+0.353	+0.426	<.001	<.001	3	6
LSCC	USP7 →	+0.303	+0.601	<.001	<.001	3	6
BRCA	PARN →	+0.361	+0.678	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,263 associations by consensus.

Exploration

TMEM186 survival (RNA) · tumor vs normal (RNA) · all TMEM186 data types