TMEM185A

Across TCGA cell cohorts, TMEM185A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,293 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM185A-associated GO terms across cancer lineages are Macroautophagy, Autophagy, and Process utilizing autophagic mechanism. Each is linked with TMEM185A in more than 14 cancer types. Because this analysis shows association rather than direction, both TMEM185A-to-partner and partner-to-TMEM185A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by TMEM185A-low versus TMEM185A-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM185A→partner) and Y-score (partner→TMEM185A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.080	+0.790	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Autophagy →	+0.071	+0.710	<.001	.002	3	14
UPPER_AERODIGESTIVE_TRACT	Process utilizing autophagic mechanism →	+0.071	+0.710	<.001	.002	3	14
LUNG_NSCLC_LUSC	Regulation of organelle assembly →	+0.047	+1.122	.005	<.001	2	15
CNS	DNA geometric change →	+0.106	+0.759	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Regulation of translation at synapse →	+0.112	+1.003	.003	.005	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,293 associations by consensus.

Macroautophagy by TMEM185A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →