TMEM184A

Across TCGA patient cohorts, TMEM184A mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM184A-associated genes across cancer lineages are Ku80, NF2, and Notch1. Each is linked with TMEM184A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM184A-to-partner and partner-to-TMEM184A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by TMEM184A-low versus TMEM184A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM184A→partner) and Y-score (partner→TMEM184A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.276	+1.710	.003	.025	3	2
UCEC	NF2 →	+0.283	+1.906	.001	.016	3	2
UCEC	Notch1 →	+0.132	+1.750	.020	.049	3	2
UCEC	PRDX1 →	+0.278	+2.000	<.001	.029	3	2
UCEC	4E-BP1 →	+0.388	+1.904	<.001	.029	3	2
UCEC	C-Raf →	+0.187	+2.222	.001	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Ku80 by TMEM184A expression — UCEC

Explore this box plot interactively →