TMEM184A

Across TCGA cell cohorts, TMEM184A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,182 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible TMEM184A-associated GO terms across cancer lineages are Negative regulation of Arp2/3 complex-mediated actin nucleation, Maintenance of unfolded protein, and Cellular response to indole-3-methanol. Each is linked with TMEM184A in more than 12 cancer types. Because this analysis shows association rather than direction, both TMEM184A-to-partner and partner-to-TMEM184A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of Arp2/3 complex-mediated actin nucleation grouped by TMEM184A-low versus TMEM184A-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM184A→partner) and Y-score (partner→TMEM184A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of Arp2/3 complex-mediated actin nucleation →	+0.149	+1.784	.008	.003	3	13
KIDNEY	Maintenance of unfolded protein →	+0.146	+1.728	.001	.002	3	13
PANCREAS	Cellular response to indole-3-methanol →	+0.249	+1.679	<.001	<.001	3	12
LARGE_INTESTINE	Glycerophospholipid metabolic process →	+0.030	+1.462	.001	.001	3	12
URINARY_TRACT	Negative regulation of inflammatory response to wounding →	+0.227	+2.723	.003	.001	3	12
URINARY_TRACT	Establishment of epithelial cell apical/basal polarity →	-0.282	-3.078	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,182 associations by consensus.

Negative regulation of Arp2/3 complex-mediated actin nucleation by TMEM184A expression — LUNG_SCLC

Explore this box plot interactively →