Across TCGA patient cohorts, TMEM179B protein abundance is significantly associated with the RNA expression of many other genes, with 7,596 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM179B-associated genes across cancer lineages are CEP78, TKFC, and COX8A. Each is linked with TMEM179B in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM179B-to-partner and partner-to-TMEM179B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM179B→partner) and Y-score (partner→TMEM179B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CEP78 →	-0.533	-0.395	.002	.003	3	4
HNSC	TKFC →	+0.529	+0.317	.008	.004	3	3
LUAD	COX8A →	+0.386	+0.443	.004	.005	3	3
PDAC	NEU1 →	+0.546	+0.443	<.001	<.001	3	3
OV	ID1 →	-1.475	-0.484	<.001	.002	3	3
HNSC	CERS2 →	+0.614	+0.359	.007	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,596 associations by consensus.

Exploration

TMEM179B survival (RNA) · tumor vs normal (RNA) · all TMEM179B data types