TMEM179

Across TCGA cell cohorts, TMEM179 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,716 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TMEM179-associated GO terms across cancer lineages are Positive regulation of autophagy of mitochondrion, Regulation of syncytium formation by plasma membrane fusion, and Vacuolar acidification. Each is linked with TMEM179 in more than 8 cancer types. Because this analysis shows association rather than direction, both TMEM179-to-partner and partner-to-TMEM179 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of autophagy of mitochondrion grouped by TMEM179-low versus TMEM179-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM179→partner) and Y-score (partner→TMEM179) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of autophagy of mitochondrion →	+0.090	+2.760	.003	.002	2	9
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.126	+4.155	<.001	<.001	3	8
OVARY	Vacuolar acidification →	+0.108	+0.664	<.001	.008	3	8
LUNG_SCLC	Regulation of myoblast fusion →	+0.120	+4.103	<.001	<.001	3	7
LUNG_SCLC	Negative regulation of myoblast fusion →	+0.116	+3.395	<.001	<.001	3	7
OVARY	Cytoplasmic translation →	+0.094	+0.973	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,716 associations by consensus.

Positive regulation of autophagy of mitochondrion by TMEM179 expression — LUNG_SCLC

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