TMEM178B

Across TCGA patient cohorts, TMEM178B RNA expression is significantly associated with the protein abundance of many other proteins, with 14,956 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM178B-associated proteins across cancer lineages are AP3B2_S272, PLS3, and PSIP1. Each is linked with TMEM178B in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM178B-to-partner and partner-to-TMEM178B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM178B versus AP3B2_S272 in LUAD, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM178B→partner) and Y-score (partner→TMEM178B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	AP3B2_S272 →	+1.291	+0.933	<.001	.004	3	6
GBM	PLS3 →	-0.601	-0.814	<.001	.001	3	4
GBM	PSIP1 →	+0.535	+0.755	.002	.005	3	4
CCRCC	PLCB4 →	+0.528	+0.860	.001	.004	3	3
HNSC	PXN_S322 →	-0.381	-0.966	.001	.006	3	3
GBM	CEMIP2 →	-0.401	-0.818	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,956 associations by consensus.

TMEM178B vs AP3B2_S272 — LUAD

Explore this scatter interactively →