TMEM178B

Across TCGA patient cohorts, TMEM178B mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM178B-associated genes across cancer lineages are CD8+ naive T-cells, lymphatic Endothelial cells, and mv Endothelial cells. Each is linked with TMEM178B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM178B-to-partner and partner-to-TMEM178B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ naive T-cells grouped by TMEM178B-low versus TMEM178B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM178B→partner) and Y-score (partner→TMEM178B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ naive T-cells →	+0.043	+2.823	.006	.036	2	1
UCEC	lymphatic Endothelial cells →	-0.031	-2.946	.026	.037	1	1
UCEC	mv Endothelial cells →	-0.034	-2.989	.012	.037	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD8+ naive T-cells by TMEM178B expression — UCEC

Explore this box plot interactively →