TMEM178B

Across TCGA cell cohorts, TMEM178B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,226 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMEM178B-associated GO terms across cancer lineages are Positive regulation of myoblast differentiation, T-helper 17 cell differentiation, and T cell selection. Each is linked with TMEM178B in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM178B-to-partner and partner-to-TMEM178B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of myoblast differentiation grouped by TMEM178B-low versus TMEM178B-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM178B→partner) and Y-score (partner→TMEM178B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of myoblast differentiation →	+0.084	+1.447	.001	.003	3	7
OVARY	T-helper 17 cell differentiation →	+0.108	+1.255	<.001	<.001	3	6
OVARY	T cell selection →	+0.141	+1.518	<.001	.001	3	6
SKIN	Establishment of protein localization to plasma membrane →	+0.090	+1.547	<.001	<.001	3	6
SKIN	Cotranslational protein targeting to membrane →	+0.128	+1.551	<.001	<.001	3	6
SKIN	Establishment of protein localization to membrane →	+0.049	+1.309	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,226 associations by consensus.

Positive regulation of myoblast differentiation by TMEM178B expression — LUNG_SCLC

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