TMEM178B

Across TCGA cell cohorts, TMEM178B protein abundance is significantly associated with the RNA expression of many other genes, with 2,111 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TMEM178B-associated genes across cancer lineages are MYBBP1A, CAD, and PHB2. Each is linked with TMEM178B in more than 6 cancer types. Because this analysis shows association rather than direction, both TMEM178B-to-partner and partner-to-TMEM178B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM178B versus MYBBP1A in LUNG_SCLC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM178B→partner) and Y-score (partner→TMEM178B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	MYBBP1A →	+0.910	+1.200	.005	<.001	3	7
BREAST	CAD →	+0.810	+0.999	.002	<.001	3	7
LUNG_SCLC	PHB2 →	+0.672	+0.837	.002	<.001	3	6
LIVER	NPTXR →	-3.210	-1.632	.001	<.001	3	6
LUNG_NSCLC_LUAD	TMEM59 →	-0.956	-1.307	.004	.003	3	6
LARGE_INTESTINE	PFAS →	+0.896	+0.921	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,111 associations by consensus.

TMEM178B vs MYBBP1A — LUNG_SCLC

Explore this scatter interactively →