TMEM178A

Across TCGA patient cohorts, TMEM178A RNA expression is significantly associated with the protein abundance of many other proteins, with 18,646 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM178A-associated proteins across cancer lineages are IKBKE, FBLN5, and VCAN_S1349. Each is linked with TMEM178A in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM178A-to-partner and partner-to-TMEM178A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM178A versus IKBKE in GBM, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM178A→partner) and Y-score (partner→TMEM178A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IKBKE →	-0.553	-0.616	<.001	.003	3	5
CCRCC	FBLN5 →	+0.724	+0.500	.001	<.001	3	5
PDAC	VCAN_S1349 →	+0.999	+0.401	.001	<.001	3	5
BRCA	MFAP4 →	+1.131	+0.518	<.001	<.001	3	5
CCRCC	VCAN →	+0.801	+0.488	.004	<.001	3	5
HNSC	DDAH1 →	+0.675	+0.799	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,646 associations by consensus.

TMEM178A vs IKBKE — GBM

Explore this scatter interactively →