TMEM178A

Across TCGA patient cohorts, TMEM178A mutation is significantly associated with the RNA expression of many other genes, with 1,578 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM178A-associated genes across cancer lineages are RNU1-44P, VN2R9P, and OR56B3P. Each is linked with TMEM178A in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM178A-to-partner and partner-to-TMEM178A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-44P grouped by TMEM178A-low versus TMEM178A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM178A→partner) and Y-score (partner→TMEM178A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU1-44P →	+0.246	+2.152	<.001	.009	3	3
CESC	VN2R9P →	+0.041	+5.201	.003	.007	3	2
UCEC	OR56B3P →	+0.156	+1.824	.001	.006	3	2
UCEC	KRTAP23-1 →	+0.241	+2.232	<.001	.007	3	2
STAD	MIR448 →	+0.311	+5.070	<.001	.004	3	2
STAD	RNU6-738P →	+0.466	+5.090	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,578 associations by consensus.

RNU1-44P by TMEM178A expression — UCEC

Explore this box plot interactively →