TMEM178A

Across TCGA cell cohorts, TMEM178A mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM178A-associated genes across cancer lineages are KRTAP4-12, IL20, and SCT. Each is linked with TMEM178A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM178A-to-partner and partner-to-TMEM178A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP4-12 grouped by TMEM178A-low versus TMEM178A-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM178A→partner) and Y-score (partner→TMEM178A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	KRTAP4-12 →	+0.046	+5.781	<.001	.001	3	1
LARGE_INTESTINE	IL20 →	+0.250	+4.247	<.001	<.001	3	1
LARGE_INTESTINE	SCT →	+0.135	+2.925	<.001	.007	3	1
LARGE_INTESTINE	ASB15 →	+0.014	+3.201	<.001	.008	1	1
LARGE_INTESTINE	EFHC2 →	+0.518	+3.333	<.001	.009	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

KRTAP4-12 by TMEM178A expression — BREAST

Explore this box plot interactively →