TMEM171

Across TCGA patient cohorts, TMEM171 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,566 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TMEM171-associated proteins across cancer lineages are PPP6R1, PSMB10_S230, and MARK2. Each is linked with TMEM171 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM171-to-partner and partner-to-TMEM171 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM171 versus PPP6R1 in BRCA, with a Pearson correlation of 0.24.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM171→partner) and Y-score (partner→TMEM171) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPP6R1 →	+0.176	+0.591	<.001	.006	3	4
LUAD	PSMB10_S230 →	+0.784	+0.986	.005	.005	3	4
HNSC	MARK2 →	+0.219	+1.077	<.001	<.001	3	4
BRCA	GBP4 →	+0.599	+0.717	<.001	<.001	3	4
COAD	CLUH →	+0.310	+1.190	<.001	<.001	2	5
BRCA	CRYBG3_S931 →	+0.484	+0.759	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,566 associations by consensus.

TMEM171 vs PPP6R1 — BRCA

Explore this scatter interactively →