TMEM171

Across TCGA cell cohorts, TMEM171 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,967 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TMEM171-associated GO terms across cancer lineages are Regulation of fibroblast proliferation, Hemostasis, and Regulation of protein maturation. Each is linked with TMEM171 in more than 9 cancer types. Because this analysis shows association rather than direction, both TMEM171-to-partner and partner-to-TMEM171 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of fibroblast proliferation grouped by TMEM171-low versus TMEM171-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM171→partner) and Y-score (partner→TMEM171) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of fibroblast proliferation →	+0.124	+2.935	.001	<.001	3	10
LUNG_NSCLC_LUSC	Hemostasis →	+0.123	+2.141	<.001	.003	3	10
LUNG_NSCLC_LUSC	Regulation of protein maturation →	+0.233	+3.504	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Positive regulation of leukocyte migration →	+0.121	+1.366	<.001	<.001	3	10
CNS	Regulation of cell-substrate adhesion →	+0.096	+2.187	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Response to osmotic stress →	+0.068	+2.217	.003	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,967 associations by consensus.

Regulation of fibroblast proliferation by TMEM171 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →