TMEM168

Across TCGA patient cohorts, TMEM168 RNA expression is significantly associated with the RNA expression of many other genes, with 20,923 significant associations in total. UVM shows the largest number of these associations.

The most reproducible TMEM168-associated genes across cancer lineages are TMEM209, PAN3, and ANAPC1. Each is linked with TMEM168 in more than 33 cancer types. Because this analysis shows association rather than direction, both TMEM168-to-partner and partner-to-TMEM168 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM168 versus TMEM209 in UVM, with a Pearson correlation of 0.93.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM168→partner) and Y-score (partner→TMEM168) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	TMEM209 →	+1.503	+1.425	<.001	<.001	3	34
UVM	PAN3 →	+1.504	+1.392	<.001	<.001	3	34
DLBC	ANAPC1 →	+1.036	+0.714	<.001	<.001	3	34
UVM	GABPA →	+1.573	+1.331	<.001	<.001	3	34
UVM	APOOL →	+1.175	+1.281	<.001	<.001	3	34
UVM	OTUD6B →	+2.037	+1.393	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,923 associations by consensus.

TMEM168 vs TMEM209 — UVM

Explore this scatter interactively →