TMEM168

Across TCGA patient cohorts, TMEM168 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,841 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM168-associated proteins across cancer lineages are TRIM24, C5AR1_S327, and GATAD2B. Each is linked with TMEM168 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM168-to-partner and partner-to-TMEM168 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM168 versus TRIM24 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM168→partner) and Y-score (partner→TMEM168) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM24 →	+0.466	+0.511	<.001	<.001	3	5
OV	C5AR1_S327 →	-1.085	-0.397	.006	.008	2	6
HNSC	GATAD2B →	+0.326	+0.823	<.001	<.001	3	5
LSCC	RBBP5 →	+0.258	+0.622	<.001	<.001	3	4
HNSC	SRP54 →	-0.242	-0.748	<.001	<.001	3	4
LSCC	THEMIS2 →	-0.402	-0.440	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,841 associations by consensus.

TMEM168 vs TRIM24 — GBM

Explore this scatter interactively →