Across TCGA patient cohorts, TMEM167B mutation is significantly associated with the RNA expression of many other genes, with 195 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM167B-associated genes across cancer lineages are RNA5SP410, SCARNA14, and FAM197Y8. Each is linked with TMEM167B in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM167B-to-partner and partner-to-TMEM167B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM167B→partner) and Y-score (partner→TMEM167B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP410 →	+0.632	+2.789	.004	.004	3	2
UCEC	SCARNA14 →	+0.566	+3.081	<.001	.001	3	2
BRCA	FAM197Y8 →	+0.014	+9.057	<.001	.003	3	1
LUAD	MIR3681 →	+0.798	+7.930	<.001	.008	3	1
HNSC	RNU6-1094P →	+0.518	+7.954	<.001	.008	3	1
HNSC	RNU6-997P →	+0.513	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 195 associations by consensus.

Exploration

TMEM167B survival (RNA) · tumor vs normal (RNA) · all TMEM167B data types