TMEM167B-DT

Across TCGA patient cohorts, TMEM167B-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 7,369 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM167B-DT-associated proteins across cancer lineages are PDLIM1_S90, MYO9B, and RBMXL1_S88. Each is linked with TMEM167B-DT in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM167B-DT-to-partner and partner-to-TMEM167B-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM167B-DT versus PDLIM1_S90 in LSCC, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM167B-DT→partner) and Y-score (partner→TMEM167B-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PDLIM1_S90 →	-0.653	-0.267	<.001	.008	3	3
CCRCC	MYO9B →	-0.254	-0.409	.001	<.001	3	3
LSCC	RBMXL1_S88 →	+0.516	+0.318	<.001	<.001	3	3
HNSC	TRIM5 →	-0.468	-0.493	<.001	.004	3	3
BRCA	ZNF638_S508 →	+0.238	+0.248	<.001	.001	3	3
GBM	AHCYL1 →	+0.373	+0.340	.001	.001	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,369 associations by consensus.

TMEM167B-DT vs PDLIM1_S90 — LSCC

Explore this scatter interactively →