TMEM167A

Across TCGA patient cohorts, TMEM167A protein abundance is significantly associated with the RNA expression of many other genes, with 8,880 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TMEM167A-associated genes across cancer lineages are DLG2, THSD7B, and RER1. Each is linked with TMEM167A in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM167A-to-partner and partner-to-TMEM167A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM167A versus DLG2 in GBM, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM167A→partner) and Y-score (partner→TMEM167A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DLG2 →	-0.878	-0.631	.002	<.001	3	4
CCRCC	THSD7B →	-1.056	-0.462	<.001	<.001	3	3
OV	RER1 →	+0.370	+0.359	.004	.003	3	3
OV	TSNARE1 →	-0.618	-0.384	.006	.007	3	3
LSCC	RPS27AP9 →	+0.456	+0.316	<.001	.001	3	3
OV	SNHG10 →	-0.484	-0.457	.009	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,880 associations by consensus.

TMEM167A vs DLG2 — GBM

Explore this scatter interactively →