TMEM164

Across TCGA cell cohorts, TMEM164 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM164-associated genes across cancer lineages are MYL10, REC114, and CD300LD. Each is linked with TMEM164 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM164-to-partner and partner-to-TMEM164 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYL10 grouped by TMEM164-low versus TMEM164-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM164→partner) and Y-score (partner→TMEM164) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYL10 →	+0.027	+5.569	<.001	.001	3	1
BLOOD_Leukemia	REC114 →	+0.101	+4.409	<.001	.005	3	1
BLOOD_Leukemia	CD300LD →	+0.507	+4.551	<.001	.004	3	1
BLOOD_Leukemia	TSSK1B →	+0.011	+4.874	<.001	.002	3	1
LARGE_INTESTINE	OR10W1 →	+0.019	+4.977	<.001	.007	3	1
BLOOD_Leukemia	SMIM32 →	+0.023	+4.169	.004	.008	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

MYL10 by TMEM164 expression — BLOOD_Leukemia

Explore this box plot interactively →