TMEM161A

Across TCGA patient cohorts, TMEM161A mutation is significantly associated with the RNA expression of many other genes, with 2,650 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM161A-associated genes across cancer lineages are IGKV2-36, AKIRIN1P2, and RPS15AP7. Each is linked with TMEM161A in more than 2 cancer types. Because this analysis shows association rather than direction, both TMEM161A-to-partner and partner-to-TMEM161A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGKV2-36 grouped by TMEM161A-low versus TMEM161A-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM161A→partner) and Y-score (partner→TMEM161A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	IGKV2-36 →	+0.298	+5.917	<.001	.001	3	3
SKCM	AKIRIN1P2 →	+0.086	+4.460	.009	<.001	3	2
LIHC	RPS15AP7 →	+0.134	+6.676	<.001	<.001	3	2
COAD	TRDJ3 →	+0.880	+4.951	<.001	.002	3	2
UCEC	RNVU1-28 →	+0.468	+1.528	.001	.005	3	2
UCEC	STK16P1 →	+0.258	+1.664	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,650 associations by consensus.

IGKV2-36 by TMEM161A expression — COAD

Explore this box plot interactively →