TMEM159

Across TCGA patient cohorts, TMEM159 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,689 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TMEM159-associated proteins across cancer lineages are AHNAK_S256, NIBAN2, and S100A11. Each is linked with TMEM159 in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM159-to-partner and partner-to-TMEM159 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM159 versus AHNAK_S256 in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM159→partner) and Y-score (partner→TMEM159) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	AHNAK_S256 →	+0.903	+0.748	<.001	<.001	3	6
GBM	NIBAN2 →	+0.455	+0.610	<.001	<.001	3	5
BRCA	S100A11 →	+0.541	+0.652	.001	.003	3	5
LSCC	CORO2A →	+0.469	+0.827	<.001	<.001	3	5
LSCC	HSPA13 →	-0.389	-0.596	<.001	<.001	3	5
LUAD	FNDC3A_S213 →	-0.534	-0.786	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,689 associations by consensus.

TMEM159 vs AHNAK_S256 — GBM

Explore this scatter interactively →