TMEM159

Across TCGA patient cohorts, TMEM159 protein abundance is significantly associated with the RNA expression of many other genes, with 7,652 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TMEM159-associated genes across cancer lineages are YIPF2, TTC39C-AS1, and SLC10A3. Each is linked with TMEM159 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM159-to-partner and partner-to-TMEM159 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM159 versus YIPF2 in OV, with a Pearson correlation of 0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM159→partner) and Y-score (partner→TMEM159) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	YIPF2 →	+1.043	+0.710	.005	<.001	3	4
HNSC	TTC39C-AS1 →	-0.523	-0.430	.001	<.001	3	4
OV	SLC10A3 →	+1.062	+0.540	.003	.005	2	4
OV	SOD1P3 →	-1.126	-0.709	.002	<.001	3	3
LSCC	CEP128 →	-0.447	-0.543	<.001	<.001	3	3
LUAD	SLC35A2 →	+0.494	+0.485	.001	.002	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,652 associations by consensus.

TMEM159 vs YIPF2 — OV

Explore this scatter interactively →