TMEM158

Across TCGA cell cohorts, TMEM158 protein abundance is significantly associated with the RNA expression of many other genes, with 282 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TMEM158-associated genes across cancer lineages are DNAJC5, SUSD1, and RIC1. Each is linked with TMEM158 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM158-to-partner and partner-to-TMEM158 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM158 versus DNAJC5 in CNS, with a Pearson correlation of -0.96.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM158→partner) and Y-score (partner→TMEM158) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	DNAJC5 →	-0.752	-1.440	.004	.004	3	1
CNS	SUSD1 →	+2.093	+1.806	.005	.003	3	1
CNS	RIC1 →	+1.030	+1.806	.004	.003	3	1
CNS	DCUN1D4 →	-1.007	-1.440	.001	.004	3	1
CNS	AIP →	-0.756	-1.806	.002	.003	3	1
CNS	SENP6 →	+0.849	+1.440	.007	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 282 associations by consensus.

TMEM158 vs DNAJC5 — CNS

Explore this scatter interactively →