TMEM151A

Across TCGA patient cohorts, TMEM151A protein abundance is significantly associated with the RNA expression of many other genes, with 1,630 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM151A-associated genes across cancer lineages are SOX10, SLC16A8, and SUN2. Each is linked with TMEM151A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM151A-to-partner and partner-to-TMEM151A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM151A versus SOX10 in GBM, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM151A→partner) and Y-score (partner→TMEM151A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SOX10 →	+1.612	+0.687	<.001	<.001	3	1
GBM	SLC16A8 →	+0.690	+0.537	<.001	<.001	3	1
GBM	SUN2 →	+0.762	+0.895	<.001	<.001	3	1
GBM	NEFH →	+1.269	+0.640	<.001	<.001	3	1
GBM	CACNA1I →	+0.646	+0.424	<.001	.009	3	1
GBM	KIAA0930 →	+0.722	+0.716	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,630 associations by consensus.

TMEM151A vs SOX10 — GBM

Explore this scatter interactively →