TMEM151A

Across TCGA patient cohorts, TMEM151A mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TMEM151A-associated genes across cancer lineages are CD4+ Tem, CD4+ Tcm, and Hepatocytes. Each is linked with TMEM151A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM151A-to-partner and partner-to-TMEM151A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tem grouped by TMEM151A-low versus TMEM151A-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM151A→partner) and Y-score (partner→TMEM151A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CD4+ Tem →	+0.032	+6.623	<.001	.019	3	1
HNSC	CD4+ Tcm →	+0.016	+5.468	<.001	.043	3	1
UCEC	Hepatocytes →	+0.017	+3.162	.006	.018	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD4+ Tem by TMEM151A expression — HNSC

Explore this box plot interactively →