TMEM151A

Across TCGA cell cohorts, TMEM151A mutation is significantly associated with the RNA expression of many other genes, with 233 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM151A-associated genes across cancer lineages are TAS2R41, NDRG4, and RPS16. Each is linked with TMEM151A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM151A-to-partner and partner-to-TMEM151A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAS2R41 grouped by TMEM151A-low versus TMEM151A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM151A→partner) and Y-score (partner→TMEM151A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TAS2R41 →	+0.025	+2.497	<.001	.001	3	2
LARGE_INTESTINE	NDRG4 →	-0.794	-2.541	.004	.005	3	1
LARGE_INTESTINE	RPS16 →	+0.398	+2.628	.002	.002	3	1
LARGE_INTESTINE	ETHE1 →	+0.909	+3.743	.002	<.001	3	1
LARGE_INTESTINE	HFE →	+0.779	+2.628	.003	.002	3	1
LARGE_INTESTINE	SH3GL2 →	+1.104	+2.837	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 233 associations by consensus.

TAS2R41 by TMEM151A expression — LARGE_INTESTINE

Explore this box plot interactively →