TMEM150A

Across TCGA cell cohorts, TMEM150A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,114 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM150A-associated GO terms across cancer lineages are Immunoglobulin heavy chain V-D-J recombination, Meiotic chromosome segregation, and Positive regulation of chromosome condensation. Each is linked with TMEM150A in more than 14 cancer types. Because this analysis shows association rather than direction, both TMEM150A-to-partner and partner-to-TMEM150A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Immunoglobulin heavy chain V-D-J recombination grouped by TMEM150A-low versus TMEM150A-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM150A→partner) and Y-score (partner→TMEM150A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Immunoglobulin heavy chain V-D-J recombination →	-0.166	-1.226	<.001	<.001	3	15
OESOPHAGUS	Meiotic chromosome segregation →	-0.146	-0.892	<.001	.002	2	15
BLOOD_Myeloma	Positive regulation of chromosome condensation →	-0.224	-1.339	<.001	<.001	3	14
KIDNEY	Regulation of mitotic sister chromatid segregation →	-0.137	-1.223	<.001	<.001	3	12
SKIN	Fatty acid beta-oxidation →	+0.087	+1.051	<.001	<.001	3	12
KIDNEY	Mitotic sister chromatid cohesion →	-0.115	-0.850	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,114 associations by consensus.

Immunoglobulin heavy chain V-D-J recombination by TMEM150A expression — KIDNEY

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