TMEM150A

Across TCGA cell cohorts, TMEM150A mutation is significantly associated with the mutation status of many other genes, with 3,216 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM150A-associated genes across cancer lineages are GRIA4, MEPE, and JAKMIP1. Each is linked with TMEM150A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM150A-to-partner and partner-to-TMEM150A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GRIA4 grouped by TMEM150A-low versus TMEM150A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM150A→partner) and Y-score (partner→TMEM150A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GRIA4 →	+3.313	+3.430	.005	.005	1	2
BLOOD_Leukemia	MEPE →	+5.635	+4.479	<.001	<.001	1	2
BLOOD_Leukemia	JAKMIP1 →	+3.635	+3.635	.003	.003	1	2
BLOOD_Leukemia	ASAP1 →	+4.050	+3.870	.002	.002	1	2
BLOOD_Leukemia	TRAPPC8 →	+3.635	+3.635	.003	.003	1	2
BLOOD_Leukemia	CACNA2D1 →	+3.050	+3.624	.001	.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,216 associations by consensus.

GRIA4 by TMEM150A expression — BLOOD_Leukemia

Explore this box plot interactively →