TMEM147

Across TCGA patient cohorts, TMEM147 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,216 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM147-associated proteins across cancer lineages are TIMM50, PAK4, and CHERP. Each is linked with TMEM147 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM147-to-partner and partner-to-TMEM147 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM147 versus TIMM50 in LSCC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM147→partner) and Y-score (partner→TMEM147) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TIMM50 →	+0.544	+0.580	<.001	<.001	3	5
OV	PAK4 →	+0.617	+0.510	.002	.001	3	4
BRCA	CHERP →	+0.291	+0.529	<.001	.005	3	4
LSCC	COIL →	+0.354	+0.514	<.001	<.001	3	4
GBM	GPATCH1 →	+0.308	+0.324	<.001	.001	3	4
OV	TBCB →	+0.326	+0.608	.007	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,216 associations by consensus.

TMEM147 vs TIMM50 — LSCC

Explore this scatter interactively →