TMEM147

Across TCGA patient cohorts, TMEM147 protein abundance is significantly associated with the RNA expression of many other genes, with 6,388 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM147-associated genes across cancer lineages are INF2, P3H4, and TNNC2. Each is linked with TMEM147 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM147-to-partner and partner-to-TMEM147 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM147 versus INF2 in LUAD, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM147→partner) and Y-score (partner→TMEM147) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	INF2 →	-0.563	-0.377	.001	.001	3	4
LUAD	P3H4 →	-0.712	-0.306	.001	.007	3	3
COAD	TNNC2 →	-2.295	-0.404	<.001	<.001	3	3
COAD	GTF2IRD1 →	-0.735	-0.230	.001	.007	3	3
CCRCC	STXBP1 →	-0.976	-0.607	<.001	<.001	3	3
LSCC	ZNF34 →	-0.422	-0.268	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,388 associations by consensus.

TMEM147 vs INF2 — LUAD

Explore this scatter interactively →