TMEM139

Across TCGA patient cohorts, TMEM139 RNA expression is significantly associated with the RNA expression of many other genes, with 17,105 significant associations in total. KIRP shows the largest number of these associations.

The most reproducible TMEM139-associated genes across cancer lineages are TMEM125, TMEM63A, and GSTK1. Each is linked with TMEM139 in more than 23 cancer types. Because this analysis shows association rather than direction, both TMEM139-to-partner and partner-to-TMEM139 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM139 versus TMEM125 in ESCA, with a Pearson correlation of 0.75.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM139→partner) and Y-score (partner→TMEM139) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	TMEM125 →	+2.396	+2.725	<.001	<.001	3	23
ESCA	TMEM63A →	+1.868	+2.636	<.001	<.001	3	23
ACC	GSTK1 →	+0.997	+1.247	<.001	<.001	2	24
CHOL	MYH14 →	+1.811	+1.527	<.001	<.001	3	23
ESCA	ANXA4 →	+1.567	+2.415	<.001	<.001	3	22
KICH	FOLR1 →	+2.734	+1.129	<.001	.006	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,105 associations by consensus.

TMEM139 vs TMEM125 — ESCA

Explore this scatter interactively →