TMEM135

Across TCGA cell cohorts, TMEM135 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,602 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TMEM135-associated GO terms across cancer lineages are Positive regulation of protein acetylation, Peroxisome organization, and Copper ion export. Each is linked with TMEM135 in more than 11 cancer types. Because this analysis shows association rather than direction, both TMEM135-to-partner and partner-to-TMEM135 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein acetylation grouped by TMEM135-low versus TMEM135-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM135→partner) and Y-score (partner→TMEM135) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of protein acetylation →	+0.110	+1.187	<.001	<.001	3	12
OESOPHAGUS	Peroxisome organization →	+0.082	+0.961	<.001	.001	3	10
PANCREAS	Copper ion export →	-0.184	-0.913	<.001	.001	3	9
LARGE_INTESTINE	Golgi organization →	+0.052	+0.843	<.001	<.001	3	9
BLOOD_Leukemia	Medulla oblongata development →	+0.182	+0.988	<.001	<.001	3	8
LIVER	Response to triglyceride →	-0.219	-1.323	.008	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,602 associations by consensus.

Positive regulation of protein acetylation by TMEM135 expression — SOFT_TISSUE

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