TMEM132E

Across TCGA patient cohorts, TMEM132E protein abundance is significantly associated with the RNA expression of many other genes, with 2,060 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM132E-associated genes across cancer lineages are OIP5, CYTH4, and KDELR3. Each is linked with TMEM132E in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM132E-to-partner and partner-to-TMEM132E results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM132E versus OIP5 in GBM, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM132E→partner) and Y-score (partner→TMEM132E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	OIP5 →	-0.510	-0.461	<.001	.001	3	2
GBM	CYTH4 →	+0.485	+0.318	.004	.007	3	1
GBM	KDELR3 →	-0.339	-0.420	.007	.006	3	1
GBM	SUSD6 →	+0.308	+0.460	.002	.001	3	1
GBM	GINS1 →	-0.457	-0.325	.004	.006	3	1
GBM	PRPF6 →	-0.234	-0.429	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,060 associations by consensus.

TMEM132E vs OIP5 — GBM

Explore this scatter interactively →