TMEM132E

Across TCGA cell cohorts, TMEM132E RNA expression is significantly associated with the go_rna of many other GO terms, with 576 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TMEM132E-associated GO terms across cancer lineages are Protein localization to nucleus, Lateral line system development, and Protein-DNA complex organization. Each is linked with TMEM132E in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM132E-to-partner and partner-to-TMEM132E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to nucleus grouped by TMEM132E-low versus TMEM132E-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM132E→partner) and Y-score (partner→TMEM132E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein localization to nucleus →	+0.032	+0.025	.005	.005	2	6
LUNG_SCLC	Lateral line system development →	+1.832	+3.441	<.001	<.001	3	5
LUNG_SCLC	Protein-DNA complex organization →	+0.048	+1.484	<.001	.002	3	5
BREAST	Negative regulation of TORC1 signaling →	+0.057	+0.266	<.001	.006	2	5
PANCREAS	Transcription initiation at RNA polymerase II promoter →	+0.030	+0.036	.005	.009	3	4
LUNG_SCLC	Promoter clearance during DNA-templated transcription →	+0.105	+2.610	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 576 associations by consensus.

Protein localization to nucleus by TMEM132E expression — PANCREAS

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