TMEM132A

Across TCGA cell cohorts, TMEM132A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,329 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TMEM132A-associated GO terms across cancer lineages are Nucleoside triphosphate metabolic process, Negative regulation of syncytium formation by plasma membrane fusion, and Post-translational protein targeting to endoplasmic reticulum membrane. Each is linked with TMEM132A in more than 10 cancer types. Because this analysis shows association rather than direction, both TMEM132A-to-partner and partner-to-TMEM132A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside triphosphate metabolic process grouped by TMEM132A-low versus TMEM132A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM132A→partner) and Y-score (partner→TMEM132A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nucleoside triphosphate metabolic process →	+0.083	+1.123	.001	.005	3	11
LUNG_SCLC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.103	+0.901	.001	.007	3	11
PANCREAS	Post-translational protein targeting to endoplasmic reticulum membrane →	+0.084	+1.210	<.001	.002	3	10
BONE	Nucleoside triphosphate biosynthetic process →	+0.084	+1.330	.006	.001	3	10
CNS	Regulation of intracellular transport →	+0.039	+0.791	<.001	.003	3	10
SKIN	Positive regulation of intracellular transport →	+0.064	+1.735	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,329 associations by consensus.

Nucleoside triphosphate metabolic process by TMEM132A expression — BONE

Explore this box plot interactively →