TMEM126B

Across TCGA patient cohorts, TMEM126B RNA expression is significantly associated with the protein abundance of many other proteins, with 8,285 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TMEM126B-associated proteins across cancer lineages are RNF214_S47, RPL14, and STIP1. Each is linked with TMEM126B in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM126B-to-partner and partner-to-TMEM126B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM126B versus RNF214_S47 in PDAC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM126B→partner) and Y-score (partner→TMEM126B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RNF214_S47 →	+0.692	+0.315	<.001	<.001	3	3
GBM	RPL14 →	-0.336	-0.277	.006	.004	2	4
OV	STIP1 →	+0.350	+0.739	<.001	<.001	3	3
HNSC	LGALS8 →	-0.255	-0.381	.003	.004	3	3
LSCC	RSF1 →	+0.279	+0.528	<.001	<.001	3	3
OV	CHORDC1 →	+0.371	+0.439	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,285 associations by consensus.

TMEM126B vs RNF214_S47 — PDAC

Explore this scatter interactively →