TMEM125

Across TCGA patient cohorts, TMEM125 protein abundance is significantly associated with the go_rna of many other GO terms, with 5 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TMEM125-associated GO terms across cancer lineages are Plasma membrane repair, Keratinocyte migration, and Response to starvation. Each is linked with TMEM125 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM125-to-partner and partner-to-TMEM125 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Plasma membrane repair grouped by TMEM125-low versus TMEM125-high in LUAD.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM125→partner) and Y-score (partner→TMEM125) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Plasma membrane repair →	+0.046	+0.810	.001	.008	3	1
LUAD	Keratinocyte migration →	+0.118	+0.835	.006	.006	3	1
LUAD	Response to starvation →	+0.026	+0.802	.008	.008	2	1
LUAD	Negative regulation of calcium ion transmembrane transport →	+0.085	+0.721	.007	.007	1	1
LUAD	Positive regulation of Wnt signaling pathway →	+0.040	+0.749	.008	.001	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Plasma membrane repair by TMEM125 expression — LUAD

Explore this box plot interactively →