Across TCGA patient cohorts, TMEM120A RNA expression is significantly associated with the protein abundance of many other proteins, with 8,712 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TMEM120A-associated proteins across cancer lineages are FIS1, HSPB1, and NUDCD3. Each is linked with TMEM120A in more than 5 cancer types. Because this analysis shows association rather than direction, both TMEM120A-to-partner and partner-to-TMEM120A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM120A→partner) and Y-score (partner→TMEM120A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FIS1 →	+0.507	+0.531	.001	<.001	3	6
LSCC	HSPB1 →	+0.516	+0.325	<.001	<.001	3	6
LUAD	NUDCD3 →	+0.240	+0.294	.001	.005	3	6
COAD	ASL →	+0.402	+0.319	<.001	.005	3	6
OV	SPR →	+0.501	+0.599	<.001	.002	3	5
OV	EIF4H →	+0.321	+0.558	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,712 associations by consensus.

Exploration

TMEM120A survival (RNA) · tumor vs normal (RNA) · all TMEM120A data types