Across TCGA patient cohorts, TMEM120A protein abundance is significantly associated with the RNA expression of many other genes, with 8,658 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM120A-associated genes across cancer lineages are STMN1, TYMS, and THOC1. Each is linked with TMEM120A in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM120A-to-partner and partner-to-TMEM120A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM120A→partner) and Y-score (partner→TMEM120A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	STMN1 →	-0.881	-0.304	.001	.001	3	4
OV	TYMS →	-0.850	-0.458	.001	<.001	3	4
LSCC	THOC1 →	-0.474	-0.267	.008	.001	3	4
LSCC	ZNF440 →	-0.713	-0.327	<.001	<.001	3	4
CCRCC	AP1S1 →	+0.472	+0.434	<.001	<.001	3	4
UCEC	NUP85 →	-0.449	-0.414	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,658 associations by consensus.

Exploration

TMEM120A survival (RNA) · tumor vs normal (RNA) · all TMEM120A data types