TMEM120A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TMEM120A mutation is significantly associated with the RNA expression of many other genes, with 389 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM120A-associated genes across cancer lineages are RNU6-192P, PRELID1P2, and LINC01853. Each is linked with TMEM120A in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM120A-to-partner and partner-to-TMEM120A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM120A→partner) and Y-score (partner→TMEM120A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIRPRNU6-192P →+0.328+4.928<.001.00532
KIRPPRELID1P2 →+0.362+4.457<.001.00532
COADLINC01853 →+0.387+7.741<.001.00932
BLCARAC1P8 →+0.069+7.640<.001.00932
UCECRN7SKP132 →+0.096+3.654<.001.00132
UCECUBE2CP4 →+0.171+2.281.008.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 389 associations by consensus.

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