Across TCGA cell cohorts, TMEM120A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,409 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TMEM120A-associated GO terms across cancer lineages are Lipid modification, Lipid catabolic process, and Nitric oxide metabolic process. Each is linked with TMEM120A in more than 8 cancer types. Because this analysis shows association rather than direction, both TMEM120A-to-partner and partner-to-TMEM120A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM120A→partner) and Y-score (partner→TMEM120A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Lipid modification →	+0.046	+1.260	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Lipid catabolic process →	+0.059	+0.839	.005	.008	3	9
SKIN	Nitric oxide metabolic process →	+0.114	+0.854	<.001	<.001	3	9
KIDNEY	Fatty acid beta-oxidation using acyl-CoA oxidase →	+0.153	+0.764	<.001	.002	3	8
BONE	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.116	-0.777	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Glycosphingolipid metabolic process →	+0.103	+1.198	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,409 associations by consensus.

Exploration

TMEM120A survival (RNA) · tumor vs normal (RNA) · all TMEM120A data types