TMEM117

Across TCGA patient cohorts, TMEM117 RNA expression is significantly associated with the RNA expression of many other genes, with 19,940 significant associations in total. ACC shows the largest number of these associations.

The most reproducible TMEM117-associated genes across cancer lineages are TWF1, SCAF11, and GTF2A1. Each is linked with TMEM117 in more than 31 cancer types. Because this analysis shows association rather than direction, both TMEM117-to-partner and partner-to-TMEM117 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM117 versus TWF1 in KICH, with a Pearson correlation of 0.85.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM117→partner) and Y-score (partner→TMEM117) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KICH	TWF1 →	+1.252	+1.100	<.001	<.001	3	32
UVM	SCAF11 →	+1.329	+1.043	<.001	<.001	3	32
UVM	GTF2A1 →	+1.321	+1.049	<.001	<.001	3	32
UVM	LEMD3 →	+1.314	+1.148	<.001	<.001	3	32
UVM	FBXO11 →	+1.470	+1.117	<.001	<.001	3	32
UVM	SENP1 →	+0.946	+1.063	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,940 associations by consensus.

TMEM117 vs TWF1 — KICH

Explore this scatter interactively →