TMEM114

Across TCGA patient cohorts, TMEM114 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TMEM114-associated genes across cancer lineages are USP9YP2. Each is linked with TMEM114 in more than 1 cancer types. Because this analysis shows association rather than direction, both TMEM114-to-partner and partner-to-TMEM114 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP9YP2 grouped by TMEM114-low versus TMEM114-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM114→partner) and Y-score (partner→TMEM114) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	USP9YP2 →	+0.054	+8.066	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

USP9YP2 by TMEM114 expression — UCEC

Explore this box plot interactively →