TMEM114

Across TCGA cell cohorts, TMEM114 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,241 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TMEM114-associated GO terms across cancer lineages are Sympathetic ganglion development, Purine nucleoside triphosphate biosynthetic process, and Purine ribonucleoside triphosphate biosynthetic process. Each is linked with TMEM114 in more than 3 cancer types. Because this analysis shows association rather than direction, both TMEM114-to-partner and partner-to-TMEM114 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sympathetic ganglion development grouped by TMEM114-low versus TMEM114-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM114→partner) and Y-score (partner→TMEM114) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Sympathetic ganglion development →	-0.264	-1.549	<.001	.001	3	4
BONE	Purine nucleoside triphosphate biosynthetic process →	+0.117	+2.089	<.001	<.001	3	3
BONE	Purine ribonucleoside triphosphate biosynthetic process →	+0.117	+2.089	<.001	<.001	3	3
BONE	Regulation of renal system process →	-0.104	-1.325	.009	.003	3	3
BONE	Positive regulation of calcium ion transport into cytosol →	-0.309	-1.483	<.001	<.001	3	3
BONE	Regulation of cell-substrate junction organization →	-0.136	-1.136	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,241 associations by consensus.

Sympathetic ganglion development by TMEM114 expression — BONE

Explore this box plot interactively →