TMEM108

Across TCGA patient cohorts, TMEM108 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,950 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TMEM108-associated proteins across cancer lineages are S100A16, ARHGEF2, and PSIP1. Each is linked with TMEM108 in more than 4 cancer types. Because this analysis shows association rather than direction, both TMEM108-to-partner and partner-to-TMEM108 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TMEM108 versus S100A16 in OV, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TMEM108→partner) and Y-score (partner→TMEM108) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	S100A16 →	-0.628	-0.793	.001	.003	3	4
LSCC	ARHGEF2 →	+0.200	+0.480	<.001	.005	3	4
GBM	PSIP1 →	+0.492	+0.734	<.001	<.001	3	4
LSCC	RERE_S656 →	+0.336	+1.118	.001	<.001	3	4
LSCC	JUNB →	-0.364	-0.719	<.001	<.001	3	4
HNSC	MYEF2 →	+0.783	+0.636	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,950 associations by consensus.

TMEM108 vs S100A16 — OV

Explore this scatter interactively →